Author: Orwoll, Benjamin E.; Sapru, Anil
Title: Biomarkers in Pediatric ARDS: Future Directions Document date: 2016_6_1
ID: 0n5apnle_1
Snippet: are based on prior definitions. Clinically, ARDS is characterized by non-cardiogenic pulmonary edema, resulting in hypoxemia and infiltrates on chest radiography (7) . Histopathologically, ARDS is characterized by a dysregulated lung inflammation and protein-rich interstitial and alveolar edema, as a consequence of enhanced permeability or disruption of the alveolar-capillary barrier (7) . Disruption of the alveolar-capillary barrier can thereby .....
Document: are based on prior definitions. Clinically, ARDS is characterized by non-cardiogenic pulmonary edema, resulting in hypoxemia and infiltrates on chest radiography (7) . Histopathologically, ARDS is characterized by a dysregulated lung inflammation and protein-rich interstitial and alveolar edema, as a consequence of enhanced permeability or disruption of the alveolar-capillary barrier (7) . Disruption of the alveolar-capillary barrier can thereby lead to protein leak and transmigration of soluble proteins and other biological mediators both from and to the systemic circulation (8) .
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