Author: Yuan, Yuan; Cao, Duanfang; Zhang, Yanfang; Ma, Jun; Qi, Jianxun; Wang, Qihui; Lu, Guangwen; Wu, Ying; Yan, Jinghua; Shi, Yi; Zhang, Xinzheng; Gao, George F.
Title: Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Document date: 2017_4_10
ID: 094lgjnn_6
Snippet: Structures of both MERS-CoV and SARS-CoV S trimers were studied by single particle cryo-EM. Strikingly, for both trimers we observed two different classes of particles during threedimensional classification, representing two conformations of the trimeric S protein with RBDs in different states (standing or lying) (Fig. 1) ......
Document: Structures of both MERS-CoV and SARS-CoV S trimers were studied by single particle cryo-EM. Strikingly, for both trimers we observed two different classes of particles during threedimensional classification, representing two conformations of the trimeric S protein with RBDs in different states (standing or lying) (Fig. 1) .
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