Selected article for: "common feature and recombinant event"
Author: Ye, Fuqiang; Han, Yifang; Zhu, Juanjuan; Li, Peng; Zhang, Qi; Lin, Yanfeng; Wang, Taiwu; Lv, Heng; Wang, Changjun; Wang, Chunhui; Zhang, Jinhai
Title: First Identification of Human Adenovirus Subtype 21a in China With MinION and Illumina Sequencers
  • Document date: 2020_4_7
    • ID: 18b2foud_58
    Snippet: Another common feature shared by HAdV21a members is the recombinant E4 gene originating from HAdV3. Products of the E4 gene could regulate cellular functions and participate in viral DNA replication and RNA processing (Weitzman, 2005) . Both phylogenetic and homology analyses provided credible evidence for this recombinant event. When this recombinant gene occurred in HAdV21a remains to be elucidated. It has been noted that highly virulent HAdV21.....
    Document: Another common feature shared by HAdV21a members is the recombinant E4 gene originating from HAdV3. Products of the E4 gene could regulate cellular functions and participate in viral DNA replication and RNA processing (Weitzman, 2005) . Both phylogenetic and homology analyses provided credible evidence for this recombinant event. When this recombinant gene occurred in HAdV21a remains to be elucidated. It has been noted that highly virulent HAdV21a could cause severe pneumonia, acute respiratory disease, and even death (Hage et al., 2014) .

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