Selected article for: "mild case and severe case"
Author: Zivcec, Marko; Scholte, Florine E. M.; Spiropoulou, Christina F.; Spengler, Jessica R.; Bergeron, Éric
Title: Molecular Insights into Crimean-Congo Hemorrhagic Fever Virus
  • Document date: 2016_4_21
    • ID: 0a20s62q_1
    Snippet: Crimean-Congo hemorrhagic fever virus (CCHFV) causes a mild to severe hemorrhagic disease (CCHF) exclusively in humans, with case fatality rates of 5%-30%. Presently, efficacy of therapeutic options in controlled clinical trials remains unproven, and supportive care remains the mainstay of treatment. CCHF endemic foci are present over a wide geographic range, including areas in Western and Central Asia, the Middle East, South-Eastern Europe, and .....
    Document: Crimean-Congo hemorrhagic fever virus (CCHFV) causes a mild to severe hemorrhagic disease (CCHF) exclusively in humans, with case fatality rates of 5%-30%. Presently, efficacy of therapeutic options in controlled clinical trials remains unproven, and supportive care remains the mainstay of treatment. CCHF endemic foci are present over a wide geographic range, including areas in Western and Central Asia, the Middle East, South-Eastern Europe, and Africa [1] [2] [3] [4] . CCHFV exists in an enzootic cycle between ticks and mammals; and geographic distribution of the virus mirrors the distribution of the primary tick vector species that include members of the Hyalomma genus (H. marginatum, H. anatolicum, H. truncatum, H. impeltatum, and H. impressum) [5] . Viral transmission to humans can occur via tick bite, or via exposure to body fluids from viremic animals or humans [3] .

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