Author: Colino, Clara I.; Millán, Carmen Gutiérrez; Lanao, José M.
Title: Nanoparticles for Signaling in Biodiagnosis and Treatment of Infectious Diseases Document date: 2018_5_31
ID: 1bxwb2hj_92
Snippet: Gold and silver nanowires have also been applied as quenchers to immobilize Molecular Beacon hairpin [94] . This structure, consisting of looped strands of DNA with a fluorophore and a fluorescence quencher at the opposite terminus, takes on its open bright state in the presence of the specific target strand of DNA or RNA. Nanowire combinations such as nanobarcodes could accomplish multiplexed assays by designing the oligonucleotides of different.....
Document: Gold and silver nanowires have also been applied as quenchers to immobilize Molecular Beacon hairpin [94] . This structure, consisting of looped strands of DNA with a fluorophore and a fluorescence quencher at the opposite terminus, takes on its open bright state in the presence of the specific target strand of DNA or RNA. Nanowire combinations such as nanobarcodes could accomplish multiplexed assays by designing the oligonucleotides of different nanowires to be complementary to target DNA sequences of different viruses, as has been demonstrated for the simultaneous detection of hepatitis A virus, hepatitis C virus, West Nile Virus, HIV and severe acute respiratory syndrome virus [112] .
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