Author: Narendrula, Rashmi; Mispel-Beyer, Kyle; Guo, Baoqing; Parissenti, Amadeo M.; Pritzker, Laura B.; Pritzker, Ken; Masilamani, Twinkle; Wang, Xiaohui; Lannér, Carita
Title: RNA disruption is associated with response to multiple classes of chemotherapy drugs in tumor cell lines Document date: 2016_2_24
ID: 0mjizsoo_12
Snippet: To assess the effect of drug dose on RNA disruption, cells were seeded into six-well plates for 24 h, following which each well was exposed to increasing doses of paclitaxel, docetaxel or carboplatin. After determining the most effective doses to induce RNA disruption, time exposure experiments were performed where cell cultures were exposed to specific drug doses for varying amounts of time (e.g. 24, 48, 72 h). Replicate experiments were perform.....
Document: To assess the effect of drug dose on RNA disruption, cells were seeded into six-well plates for 24 h, following which each well was exposed to increasing doses of paclitaxel, docetaxel or carboplatin. After determining the most effective doses to induce RNA disruption, time exposure experiments were performed where cell cultures were exposed to specific drug doses for varying amounts of time (e.g. 24, 48, 72 h). Replicate experiments were performed at least three times.
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