Author: Chen, Huanzhu; Weng, Huilan; Lin, Meirui; He, Ping; Li, Yazhen; Xie, Qingdong; Ke, Changwen; Jiao, Xiaoyang
Title: The Clinical Significance of FilmArray Respiratory Panel in Diagnosing Community-Acquired Pneumonia Document date: 2017_9_6
ID: 1awz5712_23
Snippet: Virus. In the study, the FilmArray RP detected 50 positive viruses (ADV, 3; OC43, 7; HKU1, 1; NL63, 1; MPV, 2; HRV, 9; Flu A, 8; Flu B, 2; PIV3, 4; and RSV, 13, resp.). A total of 50 (100%) of the 50 pathogens were confirmed by real-time PCR; the comparison of FilmArray RP and multiple PCR for OC43, HKU1, NL63, MPV, Flu A, Flu B, PIV3, and RSV showed satisfactory agreement (kappa > 0.7) for all positive viruses except ADV and HRV (kappa = 0; kapp.....
Document: Virus. In the study, the FilmArray RP detected 50 positive viruses (ADV, 3; OC43, 7; HKU1, 1; NL63, 1; MPV, 2; HRV, 9; Flu A, 8; Flu B, 2; PIV3, 4; and RSV, 13, resp.). A total of 50 (100%) of the 50 pathogens were confirmed by real-time PCR; the comparison of FilmArray RP and multiple PCR for OC43, HKU1, NL63, MPV, Flu A, Flu B, PIV3, and RSV showed satisfactory agreement (kappa > 0.7) for all positive viruses except ADV and HRV (kappa = 0; kappa < 0.6). In total, FilmArray RP and multiple PCR had significantly high sensitivities and specificities for the detection of respiratory viruses, but compared to the multiple PCR, the sensitivity of FilmArray RP for PIV3 and RSV was different, with sensitivity of 80% and 83.3%, respectively (Table 2) .
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