Author: Gao, George Fu; Wu, Ying
Title: Haunted with and hunting for viruses Document date: 2013_8_7
ID: 1r6kx0df_5
Snippet: Enterovirus has been known as serious human pathogens for a long time but their significance to the public health has been emphasized by the emergence of enterovirus 71 in 1998 as a serious pathogenic agents for children in Taiwan [24] and re-emerged in mainland China in 2008 [25] . In this issue, Duan and colleagues [26] summarized the findings of new enteroviruses by using NGS. Because of the application of new NGS technology they also challeng.....
Document: Enterovirus has been known as serious human pathogens for a long time but their significance to the public health has been emphasized by the emergence of enterovirus 71 in 1998 as a serious pathogenic agents for children in Taiwan [24] and re-emerged in mainland China in 2008 [25] . In this issue, Duan and colleagues [26] summarized the findings of new enteroviruses by using NGS. Because of the application of new NGS technology they also challenged the Koch's postulates. A new model of Koch's postulates, named the metagenomic Koch's postulates, has provided guidance for the study of the pathogenicity of novel viruses. The review also provided a detailed description of the NGS and related molecular methods for the virus discovery followed by a list of new enteroviruses found in human feces. These include viruses in the family of Piconaviridae, Parvoviridae, Circoviridae, Astroviridae and Polyomaviridae.
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