Selected article for: "genome size and RNA virus"
Author: Wang, Xiuqing; Christopher-Hennings, Jane
Title: Post-Transcriptional Control of Type I Interferon Induction by Porcine Reproductive and Respiratory Syndrome Virus in Its Natural Host Cells
  • Document date: 2012_5_2
    • ID: 1jmhvclq_1
    Snippet: Porcine reproductive and respiratory syndrome virus (PRRSV) is a single-stranded, positive-sense RNA virus with a genome size of approximately 15 kb. PRRSV belongs to the Arteriviridae in the order of Nidovirale. PRRSV causes acute respiratory disease in neonatal and young piglets and reproductive failure in pregnant sows. PRRSV primarily infects and destroys alveolar macrophages during acute infection of swine. In addition to macrophages, PRRSV .....
    Document: Porcine reproductive and respiratory syndrome virus (PRRSV) is a single-stranded, positive-sense RNA virus with a genome size of approximately 15 kb. PRRSV belongs to the Arteriviridae in the order of Nidovirale. PRRSV causes acute respiratory disease in neonatal and young piglets and reproductive failure in pregnant sows. PRRSV primarily infects and destroys alveolar macrophages during acute infection of swine. In addition to macrophages, PRRSV has also been identified by immunohistochemistry in dendritic-like cells in tonsils and lymph nodes [1] , suggesting that dendritic cells may either be susceptible to PRRSV or capture PRRSV by taking up apoptotic infected cells.

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