Author: Zhang, Yongli; Zhang, Hangjie; Ma, Wenqiang; Liu, Kefang; Zhao, Min; Zhao, Yingze; Lu, Xuancheng; Zhang, Fuping; Li, Xiangdong; Gao, George F.; Liu, William J.
Title: Evaluation of Zika Virus-specific T-cell Responses in Immunoprivileged Organs of Infected Ifnar1(-/-) Mice Document date: 2018_10_17
ID: km6fnf5u_13
Snippet: A previous study showed that a live ZIKV or its RNA can be detected in the semen of male patients, which indicates that the ZIKV can bypass the blood-testis barrier and replicate itself in the reproductive system 24 . Previously, we also showed that the ZIKV can cause testes damage and lead to male infertility in mice 25 . ZIKV infection can lead to viremia in rhesus monkeys, and the viral RNA can be detected in the central nervous system (CNS), .....
Document: A previous study showed that a live ZIKV or its RNA can be detected in the semen of male patients, which indicates that the ZIKV can bypass the blood-testis barrier and replicate itself in the reproductive system 24 . Previously, we also showed that the ZIKV can cause testes damage and lead to male infertility in mice 25 . ZIKV infection can lead to viremia in rhesus monkeys, and the viral RNA can be detected in the central nervous system (CNS), as well as in the visceral organs. Immunohistochemistry revealed that ZIKV-specific antigens were presented in the CNS and the multiple peripheral organs 26 . Also, in murine models, ZIKV infection can induce a robust antiviral CD8 + T-cell response in the spleen and CNS 26 .
Search related documents:
Co phrase search for related documents- blood testis and male infertility lead: 1
- blood testis and nervous system: 1
- blood testis and reproductive system: 1
- blood testis and testis damage: 1, 2
- blood testis barrier and male infertility: 1, 2
- blood testis barrier and male infertility lead: 1
- blood testis barrier and reproductive system: 1
- blood testis barrier and testis damage: 1
- blood testis barrier bypass and male infertility: 1
- blood testis barrier bypass and male infertility lead: 1
- central nervous system and CNS central nervous system detect: 1
- central nervous system and CNS present: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- central nervous system and male infertility: 1
- central nervous system and male patient: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
- central nervous system and murine model: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- central nervous system and nervous system: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- central nervous system and previous study: 1, 2, 3, 4, 5, 6
- central nervous system and reproductive system: 1, 2
- central nervous system and rhesus monkey: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date