Author: Alba Grifoni; John Sidney; Yun Zhang; Richard H Scheuermann; Bjoern Peters; Alessandro Sette
Title: Candidate targets for immune responses to 2019-Novel Coronavirus (nCoV): sequence homology- and bioinformatic-based predictions Document date: 2020_2_20
ID: 8p1agcm2_19
Snippet: Protein regions that are conserved across relatively long evolutionary distances suggest that they are structurally or functionally constrained. Vaccination strategies designed to target the immune response toward these conserved epitope regions could generate immunity that is not only crossprotective across Betacoronaviruses but also relatively resistant to ongoing virus evolution......
Document: Protein regions that are conserved across relatively long evolutionary distances suggest that they are structurally or functionally constrained. Vaccination strategies designed to target the immune response toward these conserved epitope regions could generate immunity that is not only crossprotective across Betacoronaviruses but also relatively resistant to ongoing virus evolution.
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