Author: Draz, Mohamed Shehata; Shafiee, Hadi
Title: Applications of gold nanoparticles in virus detection Document date: 2018_2_15
ID: 1xjmlwqr_9
Snippet: Furthermore, they are generally unrestricted by the practical limitations of virus isolation and propagation usually involved with other direct detection methods, such as cell culture and EM [9, 32] . Therefore, serological methods are widely accepted and recognized techniques for simple, safe, and cheap virus detection [25, 30] . In addition, they are usually described as the first choice for large-scale testing in epidemiological studies and fo.....
Document: Furthermore, they are generally unrestricted by the practical limitations of virus isolation and propagation usually involved with other direct detection methods, such as cell culture and EM [9, 32] . Therefore, serological methods are widely accepted and recognized techniques for simple, safe, and cheap virus detection [25, 30] . In addition, they are usually described as the first choice for large-scale testing in epidemiological studies and for evaluating antiviral therapies and vaccinations. However, the accuracy and reliability of serological methods are usually challenged by the cross-reactivity of the used antibodies, and the risk of false-positive results is usually very high. In addition, most immune responses can only be detected for a period of time after the initial virus infection; thus, serological detection does not normally benefit patients.
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