Author: Lee, Charlie Wah Heng; Koh, Chee Wee; Chan, Yang Sun; Aw, Pauline Poh Kim; Loh, Kuan Hon; Han, Bing Ling; Thien, Pei Ling; Nai, Geraldine Yi Wen; Hibberd, Martin L.; Wong, Christopher W.; Sung, Wing-Kin
Title: Large-scale evolutionary surveillance of the 2009 H1N1 influenza A virus using resequencing arrays Document date: 2010_2_25
ID: 1rhy8td0_31
Snippet: These ambiguous signals were caused by the presence of multiple mutations in the probe sequence, homopolymers and hybridization artefacts. We developed a novel algorithm, Evolution Surveillance and Tracking Algorithm for Resequencing arrays (EvolSTAR), to resolve this problem. EvolSTAR improves upon PBC by adding an analysis of the NHIP and nucleotide substitution bias (described below)......
Document: These ambiguous signals were caused by the presence of multiple mutations in the probe sequence, homopolymers and hybridization artefacts. We developed a novel algorithm, Evolution Surveillance and Tracking Algorithm for Resequencing arrays (EvolSTAR), to resolve this problem. EvolSTAR improves upon PBC by adding an analysis of the NHIP and nucleotide substitution bias (described below).
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