Author: Lee, Charlie Wah Heng; Koh, Chee Wee; Chan, Yang Sun; Aw, Pauline Poh Kim; Loh, Kuan Hon; Han, Bing Ling; Thien, Pei Ling; Nai, Geraldine Yi Wen; Hibberd, Martin L.; Wong, Christopher W.; Sung, Wing-Kin
Title: Large-scale evolutionary surveillance of the 2009 H1N1 influenza A virus using resequencing arrays Document date: 2010_2_25
ID: 1rhy8td0_23
Snippet: Note that since nucleotide substitution biases may vary depending on the experimental conditions, experimental reagents or input samples, for each experiment, we obtain a set of high-confidence base-calls and use them to infer the hybridization intensity reduction orders for each PM probe encoding. This is then used to compute likelihood scores for base-calling non-high-confidence query bases and mutation confirmation......
Document: Note that since nucleotide substitution biases may vary depending on the experimental conditions, experimental reagents or input samples, for each experiment, we obtain a set of high-confidence base-calls and use them to infer the hybridization intensity reduction orders for each PM probe encoding. This is then used to compute likelihood scores for base-calling non-high-confidence query bases and mutation confirmation.
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