Selected article for: "Golgi complex and rat liver"
Title: Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells
  • Document date: 1994_12_2
    • ID: 13eqppt9_52
    Snippet: We were initially surprised in this study to see such high levels of labeling for the KDEL-R in the Golgi stack and in the IC, levels which approached those seen for viral spike proteins in the Golgi complex of infected cells. However, a recent study by Wilson et al. (1993) estimated from the number of KDEL binding sites available in alkali-treated rat liver Golgi fractions that the KDEL receptor would constitute •1.3 % of the mass of total Gol.....
    Document: We were initially surprised in this study to see such high levels of labeling for the KDEL-R in the Golgi stack and in the IC, levels which approached those seen for viral spike proteins in the Golgi complex of infected cells. However, a recent study by Wilson et al. (1993) estimated from the number of KDEL binding sites available in alkali-treated rat liver Golgi fractions that the KDEL receptor would constitute •1.3 % of the mass of total Golgi membranes. These data, in conjunction with our results, indicate that the receptor is a highly abundant protein of both the Golgi complex and the IC.

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