Author: Kim, Nam-Gun; Kim, Myeong-Ae; Park, Young-Il; Jung, Tae-Sung; Son, Seong-Wan; So, ByungJae; Kang, Hwan-Goo
Title: Magnetic nanoparticle based purification and enzyme-linked immunosorbent assay using monoclonal antibody against enrofloxacin Document date: 2015_12_17
ID: 5i84nomn_1
Snippet: Fluoroquinolones (FQs) have been widely used as human and veterinary drugs, especially for the prevention and treatment of various infectious diseases in domestic animals, poultry, and fish [21] . FQs act through inhibition of DNA-gyrase, abolishing activity by interfering with the DNA rejoining reaction [3, 14] . The widespread use of FQs has led to contaminating residues in foodstuffs derived from treated animals, which can induce unwanted reac.....
Document: Fluoroquinolones (FQs) have been widely used as human and veterinary drugs, especially for the prevention and treatment of various infectious diseases in domestic animals, poultry, and fish [21] . FQs act through inhibition of DNA-gyrase, abolishing activity by interfering with the DNA rejoining reaction [3, 14] . The widespread use of FQs has led to contaminating residues in foodstuffs derived from treated animals, which can induce unwanted reactions such as erythema, burning, and itching in humans and animals [25] . Furthermore, antibiotics released into the natural ecosystem can modify the local environmental microbiota by changing the composition or activity [1, 23] . Many regulatory agencies have established a maximum residue limit for FQs in milk, meat, and other foods [5, 6] . For example, the maximum sum of enrofloxacin (ENR) and its metabolite ciprofloxacin in muscle was set at 100 ïg/kg for all animal species in the European Union [14] .
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