Author: Muhammad, Azharuddin; Toufeeq, Shahzad; Yu, Hai-Zhong; Wang, Jie; Zhang, Shang-Zhi; Li, Bing; Li, Zhen; Yang, Li-Ang; Hu, Pei; Ma, Yan; Xu, Jia-Ping
Title: Molecular Characterization of Two Mitogen-Activated Protein Kinases: p38 MAP Kinase and Ribosomal S6 Kinase From Bombyx mori (Lepidoptera: Bombycidae), and Insight Into Their Roles in Response to BmNPV Infection Document date: 2019_2_2
ID: 2s3x6sj8_28
Snippet: The Bmp38 (GenBank NM_001043531.1) and BmS6K (GenBank NM_001202528.1) were identified from transcriptome database of B. mori (Wang et al. 2016 were identified at positions 20-304, with 3 N-glycosylation and 14 ubiquitination sites (Fig. 2A) . The BmS6K cDNA contains 2,262 bp ORF encoding 753 amino acids with calculated MW of 84.5 kDa and IP of 6.45. No UTR was found in BmS6K cDNA sequence. Two S_TKc domains along with extension to Ser/Thr-type pr.....
Document: The Bmp38 (GenBank NM_001043531.1) and BmS6K (GenBank NM_001202528.1) were identified from transcriptome database of B. mori (Wang et al. 2016 were identified at positions 20-304, with 3 N-glycosylation and 14 ubiquitination sites (Fig. 2A) . The BmS6K cDNA contains 2,262 bp ORF encoding 753 amino acids with calculated MW of 84.5 kDa and IP of 6.45. No UTR was found in BmS6K cDNA sequence. Two S_TKc domains along with extension to Ser/Thr-type protein kinases domain (S_TK_x) were predicted in BmS6K amino acid sequence, with 3 N-glycosylation and 39 ubiquitination sites (Fig. 2B) . Multiple sequence alignment of Bmp38 and BmS6K with proteins of other organisms showed that Bmp38 and BmS6K include an activation loop, a conserved Thr-Glu-Tyr (TEY) and Thr-Leu-Tyr (TLY) phosphorylation motifs, respectively. Bmp38 has an ED site and a substrate-binding site. Pairwise sequence analysis of Bmp38 protein sequence shows 84.8, 91.2, 98.3, and 70.3% similarity with Drosophila melanogaster, Nasonia vitripennis, Danaus plexippus plexippus, and Homo sapiens, respectively. Similarly, the BS6K protein sequence shows 58.9, 91.5, 94.5, and 85.9% similarity with D. melanogaster, Pieris rapae, Spodoptera litura, and Papilio machaon (Fig. 3A-C) .
Search related documents:
Co phrase search for related documents- activation loop and amino acid sequence: 1
- activation loop and kinase domain: 1, 2, 3
- activation loop and sequence alignment: 1
- activation loop and sequence analysis: 1
- amino acid and cdna sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27
- amino acid and Drosophila melanogaster: 1, 2, 3
- amino acid and ED site: 1, 2
- amino acid and IP kDa: 1
- amino acid and kinase domain: 1, 2
- amino acid and organism protein: 1
- amino acid and protein sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83
- amino acid and sequence alignment: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77
- amino acid and sequence analysis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77
- amino acid and similarity show: 1, 2, 3, 4, 5, 6, 7, 8
- amino acid and substrate bind: 1
- amino acid sequence and cdna sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- amino acid sequence and Drosophila melanogaster: 1, 2
- amino acid sequence and IP kDa: 1
- amino acid sequence and protein sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78
Co phrase search for related documents, hyperlinks ordered by date