Author: Muhammad, Azharuddin; Toufeeq, Shahzad; Yu, Hai-Zhong; Wang, Jie; Zhang, Shang-Zhi; Li, Bing; Li, Zhen; Yang, Li-Ang; Hu, Pei; Ma, Yan; Xu, Jia-Ping
Title: Molecular Characterization of Two Mitogen-Activated Protein Kinases: p38 MAP Kinase and Ribosomal S6 Kinase From Bombyx mori (Lepidoptera: Bombycidae), and Insight Into Their Roles in Response to BmNPV Infection Document date: 2019_2_2
ID: 2s3x6sj8_41
Snippet: Previous reports indicate that p38 MAPK signaling involved in the cellular immune responses in mammals (Hoefen and Berk 2002) . In Drosophila, the p38 MAPK participate in host defense and protect Drosophila form injury caused by pathogens (Chen et al. 2010) . A p38 MAPK from Litopenaeus vannamei gene expression showed upregulation when challenged with pathogens (Yan et al. 2013) . Studies have shown that p38 MAPK participates in viral replication.....
Document: Previous reports indicate that p38 MAPK signaling involved in the cellular immune responses in mammals (Hoefen and Berk 2002) . In Drosophila, the p38 MAPK participate in host defense and protect Drosophila form injury caused by pathogens (Chen et al. 2010) . A p38 MAPK from Litopenaeus vannamei gene expression showed upregulation when challenged with pathogens (Yan et al. 2013) . Studies have shown that p38 MAPK participates in viral replication in in vito (Johnson et al. 2000, Khatri and Sharma 2006) . In this study, to determine Bmp38 can participate in immune response of B. mori, we analyzed Bmp38 expression after BmNPV infection.
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