Author: Neumann, Roland P.; Hilty, Markus; Xu, Binbin; Usemann, Jakob; Korten, Insa; Mika, Moana; Müller, Loretta; Latzin, Philipp; Frey, Urs
Title: Nasal microbiota and symptom persistence in acute respiratory tract infections in infants Document date: 2018_12_3
ID: 4rol2ogb_22
Snippet: Using an unsupervised approach in a representative, prospective, central European white healthy birth cohort [20] , we could show that the nasal microbiota of infection-naïve infants exhibited five distinct major microbial patterns at the onset of the first ARI, largely independent of the type of common respiratory virus. 3 weeks after the onset of the ARI, these five distinct clusters became three dominant clusters. The duration of respiratory .....
Document: Using an unsupervised approach in a representative, prospective, central European white healthy birth cohort [20] , we could show that the nasal microbiota of infection-naïve infants exhibited five distinct major microbial patterns at the onset of the first ARI, largely independent of the type of common respiratory virus. 3 weeks after the onset of the ARI, these five distinct clusters became three dominant clusters. The duration of respiratory symptoms was associated with clusters based on microbiota 3 weeks after the onset of infection, but not with commonly observed respiratory viruses, indicating close microbiota-host interactions.
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