Title: 2016 ACVIM Forum Research Abstract Program Document date: 2016_5_31
ID: 2y1y8jpx_711
Snippet: Our hypothesis was supported and we conclude that the OST can be used to predict insulin responses to grazing on pasture grass. Sepsis continues to cause high mortality in human and equine neonates. The hypothalamic-pituitary-adrenal axis is activated during sepsis to increase cortisol concentrations; however, the secretion of cortisol can be insufficient for the severity of disease in a number of sick foals. Our group and others have shown that .....
Document: Our hypothesis was supported and we conclude that the OST can be used to predict insulin responses to grazing on pasture grass. Sepsis continues to cause high mortality in human and equine neonates. The hypothalamic-pituitary-adrenal axis is activated during sepsis to increase cortisol concentrations; however, the secretion of cortisol can be insufficient for the severity of disease in a number of sick foals. Our group and others have shown that relative adrenal insufficiency (RAI), characterized by a poor cortisol response to adrenocorticotropin (ACTH), is associated with mortality and severity of disease in foals. Most studies investigating RAI in equine patients have been focused on cortisol, while other adrenocortical steroids have been overlooked.
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