Author: Sadikot, Ruxana T.; Kolanjiyil, Arun V.; Kleinstreuer, Clement; Rubinstein, Israel
Title: Nanomedicine for Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome Document date: 2017_6_27
ID: 27gutwjd_20
Snippet: Studies with other nanomicellar preparations such as 17-AAG, curcumin, and PPARγ agonists for treatment of ALI/ARDS are currently ongoing in our laboratory [8] . Together, our studies demonstrate the feasibility of translating the use of these nanomicellar preparations for translational human studies to the clinics to treat this devastating disease. We hypothesize that combinatorial administration of nanomicelles or use of more pleiotropic agent.....
Document: Studies with other nanomicellar preparations such as 17-AAG, curcumin, and PPARγ agonists for treatment of ALI/ARDS are currently ongoing in our laboratory [8] . Together, our studies demonstrate the feasibility of translating the use of these nanomicellar preparations for translational human studies to the clinics to treat this devastating disease. We hypothesize that combinatorial administration of nanomicelles or use of more pleiotropic agents that modulate multiple signaling pathways will prove to be more potent; however, further studies are needed to optimize the administration of the nanopreparations.
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