Selected article for: "dehydration vomiting and mortality morbidity"
Author: Ma, Yuanmei; Zhang, Yu; Liang, Xueya; Lou, Fangfei; Oglesbee, Michael; Krakowka, Steven; Li, Jianrong
Title: Origin, Evolution, and Virulence of Porcine Deltacoronaviruses in the United States
  • Document date: 2015_3_10
    • ID: 6o7j5k9n_1
    Snippet: The Deltacoronavirus genus has been only recently defined by genomic sequence analysis of both pig and avian isolates (15) . Since 2009, avian deltacoronaviruses have been detected in a wide range of domestic and wild birds (15) (16) (17) . The porcine deltacoronaviruses (PdCV) Hong Kong (HK) strains HKU15-155 and HKU15-44 were recently detected in rectal swabs from pigs (15) . The potential of the HKU15-155 and HKU15-44 PdCVs to cause significan.....
    Document: The Deltacoronavirus genus has been only recently defined by genomic sequence analysis of both pig and avian isolates (15) . Since 2009, avian deltacoronaviruses have been detected in a wide range of domestic and wild birds (15) (16) (17) . The porcine deltacoronaviruses (PdCV) Hong Kong (HK) strains HKU15-155 and HKU15-44 were recently detected in rectal swabs from pigs (15) . The potential of the HKU15-155 and HKU15-44 PdCVs to cause significant clinical disease in swine is not known. In mid-January 2014, PdCV was identified in fatal cases of PEDV-negative diarrhea in Ohio piglets (18) . Field reports document a history and clinical presentation (vomiting, diarrhea, and dehydration) typical of TGEV and PEDV; like for the other swine enteric CoVs, morbidity and mortality rates at PdCV-infected farms are high (18) (19) (20) (21) . In some instances, PdCV is the only virus recovered from these diarrhea outbreaks; in others, it may be present as a coinfection with PEDV. To date, outbreaks have been documented in more than 20 states in the United States. In April 2014, a PdCV strain (KOR/KNU14-04/2014) was also identified in feces from diarrheic piglets in South Korea (22) .

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