Selected article for: "acute respiratory syndrome and respiratory syndrome"
Author: Yu, Pin; Qi, Feifei; Xu, Yanfeng; Li, Fengdi; Liu, Peipei; Liu, Jiayi; Bao, Linlin; Deng, Wei; Gao, Hong; Xiang, Zhiguang; Xiao, Chong; Lv, Qi; Gong, Shuran; Liu, Jiangning; Song, Zhiqi; Qu, Yajin; Xue, Jing; Wei, Qiang; Liu, Mingya; Wang, Guanpeng; Wang, Shunyi; Yu, Haisheng; Liu, Xing; Huang, Baoying; Wang, Wenling; Zhao, Li; Wang, Huijuan; Ye, Fei; Zhou, Weimin; Zhen, Wei; Han, Jun; Wu, Guizhen; Jin, Qi; Wang, Jianwei; Tan, Wenjie; Qin, Chuan
Title: Age-related rhesus macaque models of COVID-19
  • Document date: 2020_3_30
    • ID: 3oyivuxv_1
    Snippet: In late December of 2019, a cluster of severe pneumonia cases caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) were reported from Wuhan, China. [1] [2] [3] It is critical to understand the pathogenicity of this virus for the prevention and treatment of Coronavirus disease 2019 (COVID-19). SARS-CoV-2 was isolated and classified as Betacoronavirus, belonging to the lineage B or subgenus Sarbecovirus, which also includes the huma.....
    Document: In late December of 2019, a cluster of severe pneumonia cases caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2) were reported from Wuhan, China. [1] [2] [3] It is critical to understand the pathogenicity of this virus for the prevention and treatment of Coronavirus disease 2019 (COVID-19). SARS-CoV-2 was isolated and classified as Betacoronavirus, belonging to the lineage B or subgenus Sarbecovirus, which also includes the human SARS coronavirus. 4, 5 The full virus genome of SARS-CoV-2 has about an 89% nucleotide identity with bat-SL-CoVZC45, the Spike protein has a 78% nucleotide identity with the human SARS coronavirus, and an 84% nucleotide identity with the bat-SL-CoVZC45 coronavirus. 6, 7 The SARS-infected rhesus monkey model was once established, 8 and now the SARS-CoV-2-infected rhesus monkey model can dynamically understand the pathogenicity of COVID-19.

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