Author: Tucci, Paula; Estevez, Verónica; Becco, Lorena; Cabrera-Cabrera, Florencia; Grotiuz, Germán; Reolon, Eduardo; Marín, Mónica
Title: Identification of Leukotoxin and other vaccine candidate proteins in a Mannheimia haemolytica commercial antigen Document date: 2016_9_19
ID: 71omypkg_45
Snippet: Some of the outer membrane proteins identified in this work have been reported as important immunogens and have been evaluated as recombinant subunit antigens due to their protective vaccine potential (Ayalew et al., 2011; Guzman-Brambila et al., 2012) . In particular, vaccination of mice and cattle with recombinant serotype specific antigen 1 (rSsa1) stimulated high antibody responses (Ayalew et al., 2011) . Besides, a "Best-Reciprocal-Blast-Hit.....
Document: Some of the outer membrane proteins identified in this work have been reported as important immunogens and have been evaluated as recombinant subunit antigens due to their protective vaccine potential (Ayalew et al., 2011; Guzman-Brambila et al., 2012) . In particular, vaccination of mice and cattle with recombinant serotype specific antigen 1 (rSsa1) stimulated high antibody responses (Ayalew et al., 2011) . Besides, a "Best-Reciprocal-Blast-Hit" approach was performed in order to determine that M. haemolytica outer membrane protein P6 identified in this work, is ortholog to Omp P6 of H. somni and P. multocida, both reported as Article No~e00158
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