Selected article for: "decrease expression and significant decrease expression"

Author: Jorge Blazquez-Prieto; Covadonga Huidobro; Ines Lopez-Alonso; Laura Amado-Rodriguez; Paula Martin-Vicente; Cecilia Lopez-Martinez; Irene Crespo; Cristina Pantoja; Pablo J Fernandez-Marcos; Manuel Serrano; Jacob I Sznajder; Guillermo M Albaiceta
Title: Cellular senescence limits acute lung injury induced by mechanical ventilation
  • Document date: 2020_3_25
  • ID: ebwxryai_56
    Snippet: Finally, treatment with lopinavir/ritonavir caused a non-significant decrease in Tp53 expression ( Figure 6H ) but increased Cdkn1a (p21, Figure 6I ), Plk3 ( Figure 6J) and Il6 ( Figure 6K ) expression. Therefore, treatment with lopinavir decreases Lamin-A content, impairs the changes in chromatin structure triggered by mechanical stretch and activates the p21-dependent senescence response, thus limiting apoptosis......
    Document: Finally, treatment with lopinavir/ritonavir caused a non-significant decrease in Tp53 expression ( Figure 6H ) but increased Cdkn1a (p21, Figure 6I ), Plk3 ( Figure 6J) and Il6 ( Figure 6K ) expression. Therefore, treatment with lopinavir decreases Lamin-A content, impairs the changes in chromatin structure triggered by mechanical stretch and activates the p21-dependent senescence response, thus limiting apoptosis.

    Search related documents:
    Co phrase search for related documents
    • lopinavir ritonavir treatment and mechanical stretch: 1
    • lopinavir treatment and mechanical stretch: 1
    • mechanical stretch and senescence response: 1, 2, 3
    • mechanical stretch and senescence response activate: 1