Selected article for: "potential therapeutic target and therapeutic target"
Author: Gao, Mengqi; Lin, Yi; Liu, Xing; Li, Yiming; Zhang, Chuanbao; Wang, Zheng; Wang, Zhiliang; Wang, Yulin; Guo, Zongze
Title: ISG20 promotes local tumor immunity and contributes to poor survival in human glioma
  • Document date: 2018_10_31
    • ID: 6m4q219k_21
    Snippet: In conclusion, our observations suggest that ISG20 strongly correlates with the tumor-induced immune response and infiltration of monocyte-derived macrophages and neutrophils, which increases immunity in the tumor environment. Accordingly, ISG20 may serve as a useful prognostic marker for glioma and as a potential therapeutic target. Further studies are warranted to confirm these results and unveil the underlying mechanism......
    Document: In conclusion, our observations suggest that ISG20 strongly correlates with the tumor-induced immune response and infiltration of monocyte-derived macrophages and neutrophils, which increases immunity in the tumor environment. Accordingly, ISG20 may serve as a useful prognostic marker for glioma and as a potential therapeutic target. Further studies are warranted to confirm these results and unveil the underlying mechanism.

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