Author: J Alsaadi, Entedar A; Jones, Ian M
Title: Membrane binding proteins of coronaviruses Document date: 2019_4_29
ID: 0hwbmf8k_26
Snippet: • Regardless of the precise mechanisms of membrane curvature the central role of membrane perturbation in the CoV replication cycle suggests itself as a target for designed intervention. A lack of membrane structures would clearly prevent virus replication but more reasonably even a partial inhibition might result in revelation of the replicative intermediates to the immune system and accelerate virus clearance......
Document: • Regardless of the precise mechanisms of membrane curvature the central role of membrane perturbation in the CoV replication cycle suggests itself as a target for designed intervention. A lack of membrane structures would clearly prevent virus replication but more reasonably even a partial inhibition might result in revelation of the replicative intermediates to the immune system and accelerate virus clearance.
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