Selected article for: "pathway signal and signal pathway"
Author: Lulin Huang; Yi Shi; Bo Gong; Li Jiang; Xiaoqi Liu; Jialiang Yang; Juan Tang; Chunfang You; Qi Jiang; Bo Long; Tao Zeng; Mei Luo; Fanwei Zeng; Fanxin Zeng; Shuqiang Wang; Xingxiang Yang; Zhenglin Yang
Title: Blood single cell immune profiling reveals the interferon-MAPK pathway mediated adaptive immune response for COVID-19
  • Document date: 2020_3_17
    • ID: 2okcuviq_32
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03. 15.20033472 doi: medRxiv preprint FOS is up-regulated in hospitalized patients but down-regulated in cured patients. (B) Immunofluorescence staining of IFI27 in PBMCs of patients with COVID-19 and normal controls. (C) Anti-SARS-CoV-2 response of the blood system. After the virus reaches the blood immune cells, it can activate multiple cell s.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03. 15.20033472 doi: medRxiv preprint FOS is up-regulated in hospitalized patients but down-regulated in cured patients. (B) Immunofluorescence staining of IFI27 in PBMCs of patients with COVID-19 and normal controls. (C) Anti-SARS-CoV-2 response of the blood system. After the virus reaches the blood immune cells, it can activate multiple cell subtypes of the interferon signal pathway to produce effectors, such as IFI27, IFITM1, and IFITM3, to fight the virus. Through downstream activation of MAPK, the expression of downstream effectors is activated by key transcription factors, FOS, JUN, and JUNB, which lead to a wide range of antiviral responses in the blood system. All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

    Search related documents:
    Co phrase search for related documents
    • downstream activation and MAPK downstream activation: 1, 2, 3, 4
    • downstream effector and immune cell: 1, 2, 3
    • downstream effector and key transcription factor: 1
    • downstream effector and transcription factor: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • downstream effector expression and immune cell: 1
    • downstream effector expression and transcription factor: 1
    • immune cell and key transcription factor: 1, 2, 3
    • immune cell and MAPK downstream activation: 1
    • immune cell and normal control: 1, 2, 3
    • immune cell and transcription factor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38
    • immune cell and wide range: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50
    • immunofluorescence staining and transcription factor: 1, 2, 3
    • immunofluorescence staining and wide range: 1, 2, 3, 4, 5
    • key transcription factor and transcription factor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32
    • key transcription factor and wide range: 1, 2
    • MAPK downstream activation and wide range: 1
    • normal control and transcription factor: 1
    • normal control and wide range: 1
    • transcription factor and wide range: 1, 2, 3, 4, 5, 6, 7