Selected article for: "specificity sensitivity and study purpose"
Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018
  • Document date: 2018_10_25
    • ID: 60ceejq1_310
    Snippet: A total of 135 dogs were enrolled. 5 dogs were diagnosed with hypoadrenocorticism (pre-and post-ACTH serum cortisol < 2.0 mcg/dL) and 130 dogs were diagnosed as non-hypoadrenal (NH). UCCR ranged from 0 to 1 (RR:8-24) in the hypoadrenocorticism dogs, and from 4 to > 613 in the NH group. Basal cortisol ranged from ≤ 1 to 14.7 in the NH group. For the diagnosis of hypoadrenocorticism, sensitivity and specificity of basal cortisol ≤ 1 or ≤ 2 we.....
    Document: A total of 135 dogs were enrolled. 5 dogs were diagnosed with hypoadrenocorticism (pre-and post-ACTH serum cortisol < 2.0 mcg/dL) and 130 dogs were diagnosed as non-hypoadrenal (NH). UCCR ranged from 0 to 1 (RR:8-24) in the hypoadrenocorticism dogs, and from 4 to > 613 in the NH group. Basal cortisol ranged from ≤ 1 to 14.7 in the NH group. For the diagnosis of hypoadrenocorticism, sensitivity and specificity of basal cortisol ≤ 1 or ≤ 2 were 100% and 93.1%, and 100% and 65.4% respectively. Using a cut-off of ≤ 3, UCCR was 100% sensitive and 100% specific for diagnosis of hypoadrenocorticism. UCCR is significantly more specific than basal cortisol ≤ 2 (p=0.0001) and basal cortisol ≤ 1 (p=0.0034). These results suggest that UCCR allows hypoadrenocorticism to be ruled out in more patients, compared to basal cortisol. The purpose of this prospective study was to evaluate the accuracy of Bayer Diastix® for detection of glucosuria in cat litter over 8 hours.

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