Title: 2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018 Document date: 2018_10_25
ID: 60ceejq1_383
Snippet: Interestingly, there was no correlation between % Ig-bound bacteria and the degree of scoring index (Canine IBD Activity Index; CIBDAI; 6.8 ± 3.73 (mean ± SD), r = 0.19 and Canine Chronic Enteropathy Clinical Activity Index; CCECAI; 8.2 ± 4.2, r = 0.27). Moreover, our results suggested that the IgG which bound to gut bacteria was mainly derived from local mucosal immune activity; not systemically; since serum incubation with E. coli isolates w.....
Document: Interestingly, there was no correlation between % Ig-bound bacteria and the degree of scoring index (Canine IBD Activity Index; CIBDAI; 6.8 ± 3.73 (mean ± SD), r = 0.19 and Canine Chronic Enteropathy Clinical Activity Index; CCECAI; 8.2 ± 4.2, r = 0.27). Moreover, our results suggested that the IgG which bound to gut bacteria was mainly derived from local mucosal immune activity; not systemically; since serum incubation with E. coli isolates was not different between IBD and healthy animals.
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