2018 ACVIM Forum Research Abstract Program: Seattle, Washington, June 14 - 15, 2018

R ratios of RapidTEG-TEG, TF100-TEG, and TF3700-TEG showed a significant correlation with rivaroxaban concentration measured using the anti-Xa assay (R = 0.76, P < 0.001; R = 0.82, P < 0.001; and R = 0.83, P < 0.001, respectively). fibrinogen. Due to wide inter-individual variations in plasma FVIII and VWF levels among healthy dogs, there is concern about uniformity and standard potency of CRYO to treat dogs with hemophilia A or VWD. While Greyhounds are commonly used as blood donors, previous studies have documented lower plasma VWF and fibrinogen content in Greyhounds compared to non-Greyhounds. Greyhound plasma, therefore, may not yield high potency CRYO. The objectives of this study were to determine if: 1) plasma hemostatic protein content is a good predictor of CRYO potency; 2) there is a difference in quality of CRYO prepared from Greyhounds versus non-Greyhounds; and 3) canine CRYO produced by our protocol meets human blood banking standards.