Author: Rao, Xiaoquan; Zhao, Shi; Braunstein, Zachary; Mao, Hong; Razavi, Michael; Duan, Lihua; Wei, Yingying; Toomey, Amelia C.; Rajagopalan, Sanjay; Zhong, Jixin
Title: Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways Document date: 2019_2_7
ID: 1n7xjjd5_1
Snippet: Dipeptidyl peptidase-IV (DPP4) is a single-pass type II transmembrane glycoprotein that is best known for its role as a catalytic inactivator of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) [1, 2] . In addition to its catalytic function, DPP4 interacts with a number of ligands such as adenosine deaminase (ADA), caveolin-1, Middle East respiratory syndrome coronavirus (MERS-CoV) spike protein, fibr.....
Document: Dipeptidyl peptidase-IV (DPP4) is a single-pass type II transmembrane glycoprotein that is best known for its role as a catalytic inactivator of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) [1, 2] . In addition to its catalytic function, DPP4 interacts with a number of ligands such as adenosine deaminase (ADA), caveolin-1, Middle East respiratory syndrome coronavirus (MERS-CoV) spike protein, fibronectin, and is thought to play an important role as a mediator of inflammation [3] [4] [5] [6] .
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