Clinical Features and Radiological Findings of Adenovirus Pneumonia Associated with Progression to Acute Respiratory Distress Syndrome: A Single Center Study in 19 Adult Patients

Cha, Min Jae; Chung, Myung Jin; Lee, Kyung Soo; Kim, Tae Jung; Kim, Tae Sung; Chong, Semin; Han, Jungho

In conclusion, our study demonstrates that adenovirus pneumonia is associated with high rates of ARDS and mortality in the single tertiary care setting. Adenovirus pneumonia usually manifests as multifocal or diffuse opacity on chest radiographs, and bilateral GGO and consolidation with or without pleural effusion on CT. However, we should remember that adenovirus pneumonia can also present as focal opacity with unilateral airspace lesions. Patients with adenovirus pneumonia demonstrate subsequent rapid deterioration to ARDS regardless of age and premorbid conditions; thus, aggressive treatment and careful follow-up are mandatory. In particular, patients who have progressed to ARDS are prone to show a large disease extent and high probability of pleural effusion on CT, supporting the importance of intensive imaging follow-up in patients suffering from adenovirus pneumonia.