Selected article for: "important role and protective immunity"
Author: SUN, Dongbo; WANG, Xinyu; WEI, Shan; CHEN, Jianfei; FENG, Li
Title: Epidemiology and vaccine of porcine epidemic diarrhea virus in China: a mini-review
  • Document date: 2015_11_3
    • ID: 1bt4kvxc_10
    Snippet: Genetically engineered vaccines: Mucosal immunity plays an important role in the immune mechanism of viral diarrheal diseases. Immunoglobulin A (IgA) antibodies secreted by the intestinal mucosa can defend against invading pathogens. Oral vaccines can stimulate mucosal immunity and produce protective mucosal and serum IgA antibodies, and they are an effective method for prevention of intestinal infectious diseases. For PEDV oral vaccines, Hou et .....
    Document: Genetically engineered vaccines: Mucosal immunity plays an important role in the immune mechanism of viral diarrheal diseases. Immunoglobulin A (IgA) antibodies secreted by the intestinal mucosa can defend against invading pathogens. Oral vaccines can stimulate mucosal immunity and produce protective mucosal and serum IgA antibodies, and they are an effective method for prevention of intestinal infectious diseases. For PEDV oral vaccines, Hou et al. reported that lactic acid bacteria expressing the PEDV N protein could activate the production of mucosal IgA and circulating IgG antibodies against the PEDV N protein [16] . Ge et al. reported that recombinant lactobacilli expressing * Group was defined based on the phylogenetic tree of S1 gene of the selected PEDV strains in our study (see Fig. 2 ).

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