Selected article for: "random effect and time effect"
Author: Lambert, Stephen Bernard; Ware, Robert S; Cook, Anne L; Maguire, Frances A; Whiley, David M; Bialasiewicz, Seweryn; Mackay, Ian M; Wang, David; Sloots, Theo P; Nissen, Michael D; Grimwood, Keith
Title: Observational Research in Childhood Infectious Diseases (ORChID): a dynamic birth cohort study
  • Document date: 2012_10_31
    • ID: 06e9lkwl_26
    Snippet: Primary analyses will concern the calculation of incidence rates for ARI and AGE in study children for the cohort as a whole, and by age and seasonality. The collection of control material from children when they are without symptoms will allow us to determine what proportion of ARIs and AGE can be attributed to the presence of specific pathogens. Secondary analyses will assess the incidence and shedding duration of respiratory and gastrointestin.....
    Document: Primary analyses will concern the calculation of incidence rates for ARI and AGE in study children for the cohort as a whole, and by age and seasonality. The collection of control material from children when they are without symptoms will allow us to determine what proportion of ARIs and AGE can be attributed to the presence of specific pathogens. Secondary analyses will assess the incidence and shedding duration of respiratory and gastrointestinal pathogens. Analyses will be conducted with mixed effects models with random intercepts and slope (time effect) for each participant. This method controls for the nonindependence in outcomes from the same participant at different times and allows for heterogeneity between participants.

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