Author: Wu, Joseph T.; Peak, Corey M.; Leung, Gabriel M.; Lipsitch, Marc
Title: Fractional Dosing of Yellow Fever Vaccine to Extend Supply: A Modeling Study Document date: 2016_11_10
ID: 02pjdufw_53
Snippet: In the special case where VE(1) = 1, the benefit threshold can be simplified as Next, we provide mathematical details on IAR calculations for the general case where there are m groups. Let S 0,i and I 0,i be the proportion of susceptible and infectious people in group i just before the vaccination campaign begins. Let V i be the vaccine coverage of standarddose vaccines for group i. If n i is the fractionation for group i, then vaccine coverage o.....
Document: In the special case where VE(1) = 1, the benefit threshold can be simplified as Next, we provide mathematical details on IAR calculations for the general case where there are m groups. Let S 0,i and I 0,i be the proportion of susceptible and infectious people in group i just before the vaccination campaign begins. Let V i be the vaccine coverage of standarddose vaccines for group i. If n i is the fractionation for group i, then vaccine coverage of fractional-dose vaccines for group i is V i n i . Let, be the expected number of secondary infections in group j caused by one infection in group i in a completely susceptible population. If vaccine action is all-or-nothing, the group-specific IARs are obtained by solving the equations If vaccine action is leaky, then the group-specific IARs are obtained by solving the equations
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