Selected article for: "fractional vaccine and vaccination campaign"
Author: Wu, Joseph T.; Peak, Corey M.; Leung, Gabriel M.; Lipsitch, Marc
Title: Fractional Dosing of Yellow Fever Vaccine to Extend Supply: A Modeling Study
  • Document date: 2016_11_10
    • ID: 02pjdufw_78
    Snippet: We estimate that the reproductive number of the YF epidemic in Angola during 2016 is 5·2 to 7·1. Our study is the first to provide an estimate of the transmissibility of YF in urban settings. We characterize the threshold of vaccine efficacy above which dosesparing can drastically reduce the number of YF cases. We show how the benefits of dose fractionation are influenced by the transmission intensity of the setting, the target coverage, and th.....
    Document: We estimate that the reproductive number of the YF epidemic in Angola during 2016 is 5·2 to 7·1. Our study is the first to provide an estimate of the transmissibility of YF in urban settings. We characterize the threshold of vaccine efficacy above which dosesparing can drastically reduce the number of YF cases. We show how the benefits of dose fractionation are influenced by the transmission intensity of the setting, the target coverage, and the fractional-dose vaccine efficacy and mode of action. We show that the WHO dose-sparing strategy for the Kinshasa vaccination campaign in July-August 2006 is a robust and effective strategy for reducing infection attack rate that would be robust with a large margin for error in case five-fold fractional-dose vaccine efficacy turns out to be lower than expected.

    Search related documents:
    Co phrase search for related documents
    • action mode fractional dose vaccine efficacy and vaccine efficacy: 1, 2
    • Angola YF epidemic and vaccination campaign: 1
    • Angola YF epidemic and vaccine efficacy: 1, 2, 3
    • Angola YF epidemic and YF case: 1
    • Angola YF epidemic and YF case number: 1
    • Angola YF epidemic and YF epidemic: 1, 2, 3, 4
    • Angola YF epidemic and YF transmissibility: 1
    • Angola YF epidemic reproductive number and YF epidemic: 1
    • Angola YF epidemic reproductive number and YF transmissibility: 1
    • attack rate and vaccination campaign: 1, 2, 3, 4, 5, 6
    • attack rate and vaccine efficacy: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20
    • attack rate and YF case: 1, 2
    • attack rate and YF case number: 1, 2
    • attack rate and YF epidemic: 1
    • case error large margin and vaccination campaign: 1, 2
    • case error large margin and vaccine efficacy: 1, 2
    • case error large margin and YF case: 1
    • case error large margin and YF case number: 1
    • case error large margin and YF epidemic: 1