Selected article for: "protein alignment and sequence evolution"
Author: Joana Damas; Graham M. Hughes; Kathleen C. Keough; Corrie A. Painter; Nicole S. Persky; Marco Corbo; Michael Hiller; Klaus-Peter Koepfli; Andreas R. Pfenning; Huabin Zhao; Diane P. Genereux; Ross Swofford; Katherine S. Pollard; Oliver A. Ryder; Martin T. Nweeia; Kerstin Lindblad-Toh; Emma C. Teeling; Elinor K. Karlsson; Harris A. Lewin
Title: Broad Host Range of SARS-CoV-2 Predicted by Comparative and Structural Analysis of ACE2 in Vertebrates
  • Document date: 2020_4_18
    • ID: 6ne76rh1_51
    Snippet: Phylogenetic reconstruction of the vertebrate ACE2 species tree . The multiple sequence alignment of 410 ACE2 orthologous protein sequences from mammals, birds, fishes, reptiles and amphibians was used to generate a gene tree using the maximum likelihood method of reconstruction, as implemented in IQTREE (80) . The best fit model of sequence evolution was determined using ModelFinder (81) and used to generate the species phylogeny. A total of 100.....
    Document: Phylogenetic reconstruction of the vertebrate ACE2 species tree . The multiple sequence alignment of 410 ACE2 orthologous protein sequences from mammals, birds, fishes, reptiles and amphibians was used to generate a gene tree using the maximum likelihood method of reconstruction, as implemented in IQTREE (80) . The best fit model of sequence evolution was determined using ModelFinder (81) and used to generate the species phylogeny. A total of 1000 bootstrap replicates were used to determine node support using UFBoot (82) .

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