Author: Draz, Mohamed Shehata; Shafiee, Hadi
Title: Applications of gold nanoparticles in virus detection Document date: 2018_2_15
ID: 1xjmlwqr_82
Snippet: A novel AuNP-based electrochemical assay for the molecular detection of HCMV DNA has been reported [68] . In this assay, AuNPs are applied to amplify the detected electrochemical signal by releasing many Au ions upon exposure to acid dissolution. Typically, the immobilized target HCMV ssDNA is initially labeled with oligonucleotidemodified AuNP probes followed by a metal dissolution step, releasing many gold ions. The concentration of solubilized.....
Document: A novel AuNP-based electrochemical assay for the molecular detection of HCMV DNA has been reported [68] . In this assay, AuNPs are applied to amplify the detected electrochemical signal by releasing many Au ions upon exposure to acid dissolution. Typically, the immobilized target HCMV ssDNA is initially labeled with oligonucleotidemodified AuNP probes followed by a metal dissolution step, releasing many gold ions. The concentration of solubilized gold ions is then indirectly assessed by ASV (Fig. 11B ). This assay allows the highly sensitive detection of target DNA concentrations down to 5 pM [68] .
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