Selected article for: "cell number and small number"
Author: Monika Litvinukova; Carlos Talavera-Lopez; Henrike Maatz; Daniel Reichart; Catherine L. Worth; Eric L. Lindberg; Masatoshi Kanda; Krzysztof Polanski; Eirini S. Fasouli; Sara Samari; Kenny Roberts; Elizabeth Tuck; Matthias Heinig; Daniel DeLaughter; Barbara McDonough; Hiroko Wakimoto; Joshua M. Gorham; Emily Nadelmann; Krishnaa T. Mahbubani; Kourosh Saeb-Parsy; Giannino Patone; Joseph J Boyle; Hongbo Zhang; Hao Zhang; Anissa Viveiros; Gavin Oudit; Omer Bayraktar; J. G. Seidman; Christine Seidman; Michela Noseda; Norbert Hubner; Sarah A. Teichmann
Title: Cells and gene expression programs in the adult human heart
  • Document date: 2020_4_5
    • ID: 1ilforzm_15
    Snippet: A small proportion (~1%) of cells comprised vCM5 and expressed high levels of DLC1 and EBF2 27 . These molecules participate in regulating brown adipocyte differentiation and may be involved in cardiac pacemaker activity. In addition, vCM5 nuclei had higher levels of transcripts also expressed in neural lineages ( SOX5, EBF1, and KCNAB1 ) . Notably, mice with deleted EBF1 have profound hypoplasia of the ventricular conduction system 28 . Further .....
    Document: A small proportion (~1%) of cells comprised vCM5 and expressed high levels of DLC1 and EBF2 27 . These molecules participate in regulating brown adipocyte differentiation and may be involved in cardiac pacemaker activity. In addition, vCM5 nuclei had higher levels of transcripts also expressed in neural lineages ( SOX5, EBF1, and KCNAB1 ) . Notably, mice with deleted EBF1 have profound hypoplasia of the ventricular conduction system 28 . Further confirmation and investigation of this subpopulation is required, given the small number of cells and shared marker genes with other cell types.

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