Author: Jartti, Tuomas; Smits, Hermelijn H.; Bønnelykke, Klaus; Bircan, Ozlem; Elenius, Varpu; Konradsen, Jon R.; Maggina, Paraskevi; Makrinioti, Heidi; Stokholm, Jakob; Hedlin, Gunilla; Papadopoulos, Nikolaos; Ruszczynski, Marek; Ryczaj, Klaudia; Schaub, Bianca; Schwarze, Jürgen; Skevaki, Chrysanthi; Stenberg-Hammar, Katarina; Feleszko, Wojciech
Title: Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments Document date: 2018_11_25
ID: 4svg09dt_27
Snippet: The initial response of the mucosa to RSV infection is a strong induction of antiviral type I and type III interferons and interferoninduced genes ( Figure 4A ). As RSV has developed potent mechanisms to evade this innate interferon response, the virus is able to infect most infants through RSV-NS1/2 proteins inhibiting IRF-3 and.....
Document: The initial response of the mucosa to RSV infection is a strong induction of antiviral type I and type III interferons and interferoninduced genes ( Figure 4A ). As RSV has developed potent mechanisms to evade this innate interferon response, the virus is able to infect most infants through RSV-NS1/2 proteins inhibiting IRF-3 and
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