Selected article for: "ACE activity and normal canine sequence"
Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
    • ID: 2y1y8jpx_56
    Snippet: Sixty-two dogs were evaluated. Genotypes of 38 (61%) dogs were homozygous for the DNA variant, 3 (5%) were heterozygous and 21 (34%) were homozygous for the wild type (normal canine sequence). Samples from 40 dogs were submitted for ACE analysis including 20 homozygous for the wild type and 20 homozygous for the variant. Median baseline ACE activity was significantly lower for dogs homozygous for the DNA variant (25.0 U/L) than for dogs with the .....
    Document: Sixty-two dogs were evaluated. Genotypes of 38 (61%) dogs were homozygous for the DNA variant, 3 (5%) were heterozygous and 21 (34%) were homozygous for the wild type (normal canine sequence). Samples from 40 dogs were submitted for ACE analysis including 20 homozygous for the wild type and 20 homozygous for the variant. Median baseline ACE activity was significantly lower for dogs homozygous for the DNA variant (25.0 U/L) than for dogs with the wildtype sequence (31.0 U/L) (P = 0.02).

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