Selected article for: "distribution volume and half life"

Title: 2016 ACVIM Forum Research Abstract Program
  • Document date: 2016_5_31
  • ID: 2y1y8jpx_631
    Snippet: After IV dosing, volume of distribution (V SS ) was 1.9 (0.3) L/kg (mean, std. deviation), terminal half-life (t½) was 39.4 (15.9) hours, and clearance was 28.1 (17.3) mL/kg/hr. After oral dosing, peak concentration (C MAX ) was 1.2 (0.5) µg/mL and terminal t½ was 38.1 (15.0) hours. Bioavailability from oral administration was 15.9% (8.6) . No adverse effects were observed from either route of administration......
    Document: After IV dosing, volume of distribution (V SS ) was 1.9 (0.3) L/kg (mean, std. deviation), terminal half-life (t½) was 39.4 (15.9) hours, and clearance was 28.1 (17.3) mL/kg/hr. After oral dosing, peak concentration (C MAX ) was 1.2 (0.5) µg/mL and terminal t½ was 38.1 (15.0) hours. Bioavailability from oral administration was 15.9% (8.6) . No adverse effects were observed from either route of administration.

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