Author: Folarin, Onikepe A.; Ehichioya, Deborah; Schaffner, Stephen F.; Winnicki, Sarah M.; Wohl, Shirlee; Eromon, Philomena; West, Kendra L.; Gladden-Young, Adrianne; Oyejide, Nicholas E.; Matranga, Christian B.; Deme, Awa Bineta; James, Ayorinde; Tomkins-Tinch, Christopher; Onyewurunwa, Kenneth; Ladner, Jason T.; Palacios, Gustavo; Nosamiefan, Iguosadolo; Andersen, Kristian G.; Omilabu, Sunday; Park, Daniel J.; Yozwiak, Nathan L.; Nasidi, Abdusallam; Garry, Robert F.; Tomori, Oyewale; Sabeti, Pardis C.; Happi, Christian T.
Title: Ebola Virus Epidemiology and Evolution in Nigeria Document date: 2016_10_15
ID: 2g9ggwog_45
Snippet: in our data in Figure 2A , in which multiple successive links in the chain share identical genomes. In addition, when mutations do occur, >1 can arise in a single patient, making genetic distance an imperfect guide to the number of transmission links that have occurred. Thus, most of the cases infected directly by the index patient in Nigeria had identical genomes, but 1 case (case 4) differed by 4 mutations, even though it too resulted from a si.....
Document: in our data in Figure 2A , in which multiple successive links in the chain share identical genomes. In addition, when mutations do occur, >1 can arise in a single patient, making genetic distance an imperfect guide to the number of transmission links that have occurred. Thus, most of the cases infected directly by the index patient in Nigeria had identical genomes, but 1 case (case 4) differed by 4 mutations, even though it too resulted from a single transmission. Contact tracing ( Figure 2B )-when it is available-does not suffer from such limitations.
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