Author: Ayodeji, Mobolanle; Kulka, Michael; Jackson, Scott A; Patel, Isha; Mammel, Mark; Cebula, Thomas A; Goswami, Biswendu B
Title: A Microarray Based Approach for the Identification of Common Foodborne Viruses Document date: 2009_3_19
ID: 7s5b3lpn_20
Snippet: To further explore genotype/subgenotype differentiation, different HAV strains belonging to the same subgenotype Ib sequence (Fig. 1, group 1) were hybridized to the array. As shown in Fig. (5) , HAV strains HM175 wt, clone 1 and 18f hybridize most efficiently to genotype Ib (consensus group 1) probes (hav1Cb). Lower efficiencies of hybridization are observed for all three targets against all other probe sets. These results reflect a greater targ.....
Document: To further explore genotype/subgenotype differentiation, different HAV strains belonging to the same subgenotype Ib sequence (Fig. 1, group 1) were hybridized to the array. As shown in Fig. (5) , HAV strains HM175 wt, clone 1 and 18f hybridize most efficiently to genotype Ib (consensus group 1) probes (hav1Cb). Lower efficiencies of hybridization are observed for all three targets against all other probe sets. These results reflect a greater target specificity for the probe set that contains target member sequences than for the other genotype Ib derived probe set (hav2b) that does not contain target member sequences (group 2 in Fig. 1) . For all target strains, the remaining probe sets yielded signal intensities equivalent to or less than intensities for probe set hav2b. Thus, in support of the interpretation of results of Fig. (4) , this array has the potential to discriminate viral targets at the level of both their genotype and subgenotype.
Search related documents:
Co phrase search for related documents- efficiently hybridize and ib sequence: 1
- efficiently hybridize and subgenotype genotype: 1
- efficiently hybridize and subgenotype genotype level: 1
- efficiently hybridize and target strain: 1
- genotype subgenotype and ib sequence: 1, 2
- genotype subgenotype and probe set: 1
- genotype subgenotype and subgenotype genotype: 1, 2, 3, 4
- genotype subgenotype and subgenotype genotype level: 1
- genotype subgenotype and subgenotype ib sequence: 1
- genotype subgenotype and target strain: 1
- hav1Cb probe and probe set: 1, 2, 3, 4
- hav1Cb probe and signal intensity: 1
- hav1Cb probe and target strain: 1, 2
- hav1Cb probe and viral target: 1
- hybridization low efficiency and low efficiency: 1, 2
- ib sequence and subgenotype genotype: 1, 2
- ib sequence and subgenotype genotype level: 1
- ib sequence and subgenotype ib sequence: 1
- ib sequence and target strain: 1
Co phrase search for related documents, hyperlinks ordered by date