A Pneumonia Case Associated with Type 2 Polio Vaccine Strains

Li, Mao-Zhong; Zhang, Tie-Gang; Li, Ai-Hua; Luo, Ming; Jiao, Yang; Dong, Mei; Gong, Cheng; Huang, Fang

On July 23, 2015, 18 days after his second dose of tOPV, he developed a fever, concomitant cough, some phlegm, and his body temperature reached 40°C. An antibiotic was given by intravenous drip for 3 days in a local hospital in Anhui Province, but a low-grade fever and cough persisted until his hospitalization in Beijing Haidian Hospital. Blood tests in the Haidian Hospital revealed the following results: the total white blood cell count was 1.165 × 10 10 /L (normal range: 1.500 × 10 10 /L-2.000 × 10 10 /L); N: 14.8%; the total platelet count was 7 × 10 11 /L; and hemoglobin was 110 g/L. The laboratory tests showed that the C-reactive protein was 5.0 mg/L (normal range ≤10.0 mg/L). Chest radiographs showed thickness or turbulence in the texture in both lungs and blotches of shadows in the right lung. Further clinical features were respiratory sounds and pulmonary rales. In the hospital, treatments included antibiotic therapy and respiratory management such as aerosols, suctioning, back therapy, and body positioning. He was given intravenous tazobactam sodium 1 g/d and ambroxol hydrochloride and Ge injections 15 mg/d. After 3 days of treatment, his body temperature returned to normal and his cough was mild. He was released on August 8 after his cough and pulmonary rales disappeared and after the chest films revealed significant absorption of the infected lesions. Except for the presence of the pneumonia symptoms, he had no problems with his growth and development.