Author: Theis, Corinna; Reeder, Jens; Giegerich, Robert
Title: KnotInFrame: prediction of -1 ribosomal frameshift events Document date: 2008_9_27
ID: 4ov0j2u3_40
Snippet: We compared the predictions of KnotInFrame to the predictions of (5) on the S. cerevisiae genome. This comparison serves several purposes: since the reference set of verified signals in the RECODE DB is rather small, we use the predictions of (5) as extended test set. Of course, it is neither guaranteed nor expected that all of their predictions are in fact real frameshift events. However, a matching prediction of both approaches at a certain loc.....
Document: We compared the predictions of KnotInFrame to the predictions of (5) on the S. cerevisiae genome. This comparison serves several purposes: since the reference set of verified signals in the RECODE DB is rather small, we use the predictions of (5) as extended test set. Of course, it is neither guaranteed nor expected that all of their predictions are in fact real frameshift events. However, a matching prediction of both approaches at a certain location strengthens the plausibility of this site. On the other hand, contradicting predictions may hint at a weak spot of either of the two approaches. We will show and discuss examples of each of these cases.
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