Author: Munday, Diane C.; Emmott, Edward; Surtees, Rebecca; Lardeau, Charles-Hugues; Wu, Weining; Duprex, W. Paul; Dove, Brian K.; Barr, John N.; Hiscox, Julian A.
Title: Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus Document date: 2010_7_20
ID: 2zhaknbi_35
Snippet: Alterations in Mitochondrial Protein Abundance and Mitochondrial Integrity in HRSV-infected Cells-As highlighted by the canonical pathway analysis, mitochondrial proteins formed a group whose abundance differed between HRSVinfected and mock-infected cells. This had not been observed previously. Mitochondrial proteins were identified and quantified in both the nuclear and cytoplasmic fractions as being both ablated and enriched proteins in HRSV-in.....
Document: Alterations in Mitochondrial Protein Abundance and Mitochondrial Integrity in HRSV-infected Cells-As highlighted by the canonical pathway analysis, mitochondrial proteins formed a group whose abundance differed between HRSVinfected and mock-infected cells. This had not been observed previously. Mitochondrial proteins were identified and quantified in both the nuclear and cytoplasmic fractions as being both ablated and enriched proteins in HRSV-infected cells compared with mock-infected cells (supplemental Tables 1-3) . This is presented diagrammatically in Fig. 6 with the proteins arranged according to their localization in the mitochondria.
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