Selected article for: "abrupt discontinuation and long term treatment"

Author: Sakthivel, Muthukumar; Elkashif, Sami; Al Ansari, Khalid; Powell, Colin V.E.
Title: Rebound stridor in children with croup after nebulised adrenaline: does it really exist?
  • Document date: 2019_3_23
  • ID: 5er37cdx_5
    Snippet: Rebound is defined as a temporary deviation from a normal state in the opposite direction following an abrupt removal or discontinuation of a variable, such as a treatment suddenly discontinued after long-term use, a passive resistance that is released suddenly, an undershoot in an effort to restore balance or homeostasis, or a condition wherein the maximum therapeutic effect is reached and the opposite effect ensues [9] . The rebound phenomenon .....
    Document: Rebound is defined as a temporary deviation from a normal state in the opposite direction following an abrupt removal or discontinuation of a variable, such as a treatment suddenly discontinued after long-term use, a passive resistance that is released suddenly, an undershoot in an effort to restore balance or homeostasis, or a condition wherein the maximum therapeutic effect is reached and the opposite effect ensues [9] . The rebound phenomenon occurs when the sudden discontinuation of a medication results in the relapse of symptoms that are worse than those before the treatment. Examples of rebound phenomenon include Stewart-Holmes test for cerebellar lesions [10] and Somogyi phenomenon [11] .

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