Author: Tuplin, A.; Evans, D. J.; Buckley, A.; Jones, I. M.; Gould, E. A.; Gritsun, T. S.
Title: Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus Document date: 2011_5_27
ID: 0aiaklrn_2
Snippet: Flavivirus virions are $50-nm particles with a nucleocapsid composed of capsid (C) protein surrounding a positive-sense single-stranded RNA genome of $11 kb. The capsid is enclosed in a lipid membrane within which the viral membrane (M) and envelope (E) proteins are embedded. The genome encodes a single polyprotein of approximately 3400 amino acids from which the three structural (C, M and E) and seven non-structural (NS1, NS2A, NS2B, NS3, NS4A, .....
Document: Flavivirus virions are $50-nm particles with a nucleocapsid composed of capsid (C) protein surrounding a positive-sense single-stranded RNA genome of $11 kb. The capsid is enclosed in a lipid membrane within which the viral membrane (M) and envelope (E) proteins are embedded. The genome encodes a single polyprotein of approximately 3400 amino acids from which the three structural (C, M and E) and seven non-structural (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5) proteins are processed by cellular and viral proteases (8) .
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